Wednesday, July 22, 2009

Coming soon ... drugs absorbed via contact lenses

Scientists have been working toward addressing the fact that up to 59 percent of glaucoma patients regularly skip their drops, even though untreated glaucoma can lead to blindness.

A possible solution is a method that utilizes the contact lens to dispense the drug into the body.

According to the wired.com article:
Researchers have been working for nearly a decade on drug-dispensing contact lenses that could deliver eye medication more effectively, but they've struggled to design a lens that releases a continuous supply of the meds. Now, scientists report that they've created a contact lens that can deliver a high concentration of antibiotic at a constant rate for more than 30 days.

Apparently, doughnut shape of drug-containing portion of the lens allows the drug to be absorbed without affecting the wearer's vision.
To make their lens, the researchers took a biodegradable polymer called PLGA and dissolved it in an organic solvent, and then they added their drug. As the solvent evaporated, they were left with drug mixed into a polymer film. Finally, they coated the film in a hydrogel called pHEMA, which is the same material that’s used to make regular contact lenses.

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